Evidence supporting the use of: Greater Celandine
For the health condition: Canker Sores
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Greater Celandine (Chelidonium majus) has a long history of use in traditional herbal medicine for various skin and mucosal conditions, including canker sores (aphthous ulcers). In European folk medicine, the fresh yellow-orange latex from the stem is sometimes applied directly to minor wounds, warts, and mouth ulcers, stemming from the plant’s reputation as a topical remedy for skin and mucous membrane disorders. The rationale behind this traditional use is likely due to Greater Celandine’s known antimicrobial, anti-inflammatory, and analgesic properties, as observed in laboratory studies of its alkaloids (such as chelidonine and sanguinarine). However, direct evidence from modern clinical trials evaluating the efficacy and safety of Greater Celandine specifically for canker sores is lacking. Most of the available literature consists of historical use and in vitro studies demonstrating antimicrobial activity, rather than rigorous clinical evaluations. Therefore, while there is a basis for its use in folk medicine and some pharmacological plausibility, the overall evidence remains weak and primarily anecdotal. Caution is also warranted due to potential toxicity and irritation, especially with internal use. In summary, Greater Celandine’s use for canker sores is supported by tradition and some pharmacological rationale, but not by robust clinical evidence.
Other ingredients used for Canker Sores
aloe verabamboo
basil
myrobalan
betel
bisabolol
blackberry
bасора
chamomile
clove
coating
coconut milk
Coptis chinensis
curcumin
dog rose
folate
ginger
horseradish
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
magnesium
milk
mustard seed
spruce
omega-3 fatty acids
oregano
oregon grape
parsley
peppermint oil
pineapple
plantain
rhizome
sage
schizonepeta
scrophularia root
slippery elm bark
sphaeranthus indicus
thyme
triphala
vitamin B12
vitamin C
zinc
yellow root
squawvine
chickweed
typhonium
xanthium (cockleburs)
papaya
neem tree
nut grass
clerodendrum indicum
ferula assafoetida
commiphora
blackboard tree
boxthorne
buckthorn
lemongrass
myrrh
siler root
hyacinth bean
morinda
oriental arborvitae
trichosanthes
zanthoxylum
sheep's sorrel
eucalyptus
menthol oil
aster root
paw paw
herbal blend (proprietary)
indigo leaves
Ash
Avens
Agastache
Ardisia
acacia
Agrimony
Achyranthes
Anamu
American Liverleaf
Agrimonia pilosa
Asteracea
Acemannan
Amor seco
Arisaema
Bee Propolis
Bermuda Grass
Blue Flag
Bai Ji
Baphicacanthus cusia
Bidens pilosa
Blackthorn
Bicarbonate
Balsam
Bishop's Weed
Bayleaf
Black galingale
Barleria
Bitter Grass
Bloodroot
Banyan
Bee products
Black Nightshade
Bombax
Borassus aethiopum
Bacteria
Bassia scoparia
Borneol
Coconut
Curry leaf
Calendula
Clerodendrum trichotomum
Chlorophyllin
Carvacrol
Capillary Artemisia
Citron
Capsaicin
Cajuput
Chinese Raisintree
Cowherb
Centipeda
Cistus
Corktree
Collinsonia
Copaiba Oil
Celosia
Chrysophanics
Dianthus
DIVI-DIVI
Dragonhead
David's Milkberry
European Elder
Eupolyphaga sinensis
Eclipta
Essential Oil Blend
Euphorbia
European-Five Finger Grass
Embelia
Eugenol
Flueggea suffruticosa
Fuchsia
Fang-Feng
Ficus simplicissima
Frankincense
Gnaphalium
Glycolic acid
Guava
Giant Blazingstar
Glechoma hederacea
Gallotannin
Galangal
Guazuma ulmifolia
Little ironweed
Mustard
Mallow
Oak
Rose
Snakeroot (unspecified)
Sandalwood
Sumac
Other health conditions supported by Greater Celandine
Abdominal PainAcid Indigestion
Appetite (deficient)
Bites and Stings
Bleeding (external)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Canker Sores
Cuts
Digestion (poor)
Dyspepsia
Gastritis
Jaundice (adults)
Liver Detoxification
Lymph Nodes or Glands (swollen)
Pain (general remedies for)
Skin (infections)
Ulcers
Wounds and Sores