Evidence supporting the use of: Black Nightshade
For the health condition: Canker Sores
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Black Nightshade (Solanum nigrum) has a long history of use in various traditional medicine systems, especially in Ayurveda, Traditional Chinese Medicine, and some African folk remedies. In these systems, Black Nightshade has been employed for its purported anti-inflammatory, analgesic, and wound-healing properties. Specifically, it has sometimes been recommended as a topical application or as a rinse to help alleviate mouth ulcers, including canker sores (aphthous ulcers). The rationale is based on the plant’s reputed cooling and healing effects, which are believed to soothe mucosal tissues and reduce inflammation.
However, direct scientific evidence supporting the efficacy of Black Nightshade for canker sores is very limited. While in vitro and animal studies have suggested that extracts of Solanum nigrum possess anti-inflammatory and antimicrobial properties, there are no well-designed clinical trials or pharmacological studies specifically evaluating its use for aphthous ulcers or canker sores in humans. Most references to its use for this purpose are anecdotal or found in ethnobotanical literature, not in peer-reviewed medical research.
Furthermore, Black Nightshade contains potentially toxic alkaloids, and its safety profile—particularly for oral use—has not been well established. Thus, while its use is rooted in tradition, scientific validation is lacking, and caution is warranted due to possible toxicity.
Other ingredients used for Canker Sores
aloe verabamboo
basil
myrobalan
betel
bisabolol
blackberry
bасора
chamomile
clove
coating
coconut milk
Coptis chinensis
curcumin
dog rose
folate
ginger
horseradish
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
magnesium
milk
mustard seed
spruce
omega-3 fatty acids
oregano
oregon grape
parsley
peppermint oil
pineapple
plantain
rhizome
sage
schizonepeta
scrophularia root
slippery elm bark
sphaeranthus indicus
thyme
triphala
vitamin B12
vitamin C
zinc
yellow root
squawvine
chickweed
typhonium
xanthium (cockleburs)
papaya
neem tree
nut grass
clerodendrum indicum
ferula assafoetida
commiphora
blackboard tree
boxthorne
buckthorn
lemongrass
myrrh
siler root
hyacinth bean
morinda
oriental arborvitae
trichosanthes
zanthoxylum
sheep's sorrel
eucalyptus
menthol oil
aster root
paw paw
herbal blend (proprietary)
indigo leaves
Ash
Avens
Agastache
Ardisia
acacia
Agrimony
Achyranthes
Anamu
American Liverleaf
Agrimonia pilosa
Asteracea
Acemannan
Amor seco
Arisaema
Bee Propolis
Bermuda Grass
Blue Flag
Bai Ji
Baphicacanthus cusia
Bidens pilosa
Blackthorn
Bicarbonate
Balsam
Bishop's Weed
Bayleaf
Black galingale
Barleria
Bitter Grass
Bloodroot
Banyan
Bee products
Black Nightshade
Bombax
Borassus aethiopum
Bacteria
Bassia scoparia
Borneol
Coconut
Curry leaf
Calendula
Clerodendrum trichotomum
Chlorophyllin
Carvacrol
Capillary Artemisia
Citron
Capsaicin
Cajuput
Chinese Raisintree
Cowherb
Centipeda
Cistus
Corktree
Collinsonia
Copaiba Oil
Celosia
Chrysophanics
Dianthus
DIVI-DIVI
Dragonhead
David's Milkberry
European Elder
Eupolyphaga sinensis
Eclipta
Essential Oil Blend
Euphorbia
European-Five Finger Grass
Embelia
Eugenol
Flueggea suffruticosa
Fuchsia
Fang-Feng
Ficus simplicissima
Frankincense
Gnaphalium
Glycolic acid
Guava
Giant Blazingstar
Glechoma hederacea
Gallotannin
Galangal
Guazuma ulmifolia
Little ironweed
Mustard
Mallow
Oak
Rose
Snakeroot (unspecified)
Sandalwood
Sumac
Other health conditions supported by Black Nightshade
Abdominal PainAbscesses
Acid Indigestion
Anal Fistula or Fissure
Anemia
Arthritis
Asthma
Bites and Stings
Bleeding (external)
Boils
Bronchitis
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Chicken Pox
Chills
Cholera
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Colitis
Cuts
Diarrhea
Dysentery
Dyspepsia
Eczema
Eye Infections
Fever
Fungal Infections
Gall Bladder (sluggish or removed)
Gangrene
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Headache (general)
Headache (sinus)
Hemorrhoids
Infection
Infection (bacterial)
Inflammation
Itching
Kidney Infection
Leprosy
Lesions
Lice
Liver Detoxification
Lymph Nodes or Glands (swollen)
Malaria
Nausea and Vomiting