Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Centipeda, most commonly referring to Centipeda minima, is a herb used in traditional medicine systems, particularly in Chinese medicine, where it is known as Erdexian (ground spikenard). In Traditional Chinese Medicine (TCM), Centipeda minima has been employed for centuries to support respiratory health and is believed to help "disperse wind-cold" and "resolve phlegm." It is often included in formulations intended to relieve symptoms such as cough, nasal discharge, and bronchitis. The traditional use is grounded in empirical observations and historical practice, rather than rigorous scientific validation.

Scientific studies on Centipeda minima regarding bronchitis are limited, with most research focused on its anti-inflammatory, anti-allergic, and antimicrobial properties in vitro or in animal models. Some constituents, such as sesquiterpene lactones, have demonstrated biological activity relevant to respiratory inflammation, but direct clinical evidence in humans with bronchitis is lacking. Thus, while there is a rational basis for its use from the perspective of traditional medicine and some supportive preclinical data, high-quality clinical trials confirming its efficacy and safety for bronchitis are not available. The evidence is therefore rated as a 2: supported by tradition and limited preclinical research, but lacking robust scientific validation.

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