Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phellodendron amurense, also known as Amur cork tree, has a long history of use in Traditional Chinese Medicine (TCM). It is often included in herbal formulations aimed at treating "damp-heat" conditions, which can encompass symptoms analogous to hemorrhoids—such as swelling, bleeding, and discomfort in the anal region. The bark of Phellodendron amurense contains several alkaloids, most notably berberine, which has demonstrated anti-inflammatory and antimicrobial properties in laboratory studies. However, direct clinical studies specifically evaluating the efficacy of Phellodendron amurense for hemorrhoids are lacking.

Most of the justification for its use in hemorrhoid management comes from traditional practice and the herb’s reputed ability to reduce inflammation and control bleeding. It is commonly combined with other botanicals like Coptis chinensis and Scutellaria baicalensis in TCM formulas. Scientific evidence for its effectiveness in treating hemorrhoids is limited to animal studies and in vitro experiments that highlight its anti-inflammatory and vascular-protective effects. There are no high-quality, randomized controlled trials in humans directly assessing its use for hemorrhoids. Thus, the evidence base is mainly traditional, with a modest pharmacological rationale but little to no direct clinical support.

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