Evidence supporting the use of: Magnesium
For the health condition: Apathy

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Magnesium is an essential mineral involved in numerous physiological processes, including neurotransmitter release, energy production, and regulation of neuronal excitability. There is scientific interest in magnesium's role in neuropsychiatric conditions, particularly because magnesium deficiency has been linked with symptoms such as apathy, depression, and fatigue. Several observational studies have found that low magnesium levels are associated with increased risk of mood disturbances, including apathy, especially in elderly populations. Additionally, magnesium is an important cofactor for enzymes involved in the synthesis of neurotransmitters like serotonin and dopamine, which play key roles in motivation and mood regulation.

However, high-quality clinical trials specifically investigating magnesium supplementation for the treatment of apathy are limited. Some studies on depression and chronic fatigue syndrome report improvements in mood and energy with magnesium supplementation, which may indirectly suggest benefits for apathy, but these studies often have methodological limitations and do not assess apathy as a primary outcome. There is emerging evidence that correcting magnesium deficiency can improve neuropsychiatric symptoms, but direct evidence for its efficacy in treating apathy is weak.

In summary, while there is a plausible biological rationale and some indirect scientific evidence supporting the use of magnesium in neuropsychiatric symptoms that overlap with apathy, robust clinical evidence is lacking. Therefore, the scientific justification for magnesium supplementation specifically for apathy is limited, and more targeted research is needed.

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Other health conditions supported by magnesium

Addictions (drugs)
Addictions (general remedies for)
Aging (prevention)
Alcoholism
Alkalosis
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Control (countering side effects)
Body Building
Body Odor
Boils
Broken Bones
Bronchitis
Bulimia
Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Colon (atonic)
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Exercise
Fatigue
Fibromyalgia Syndrome
Headache (cluster)
Headache (tension)
Hearing Loss
Heart (weakness)
Mental Illness
Migraine
Mood Swings
Muscle Tone (lack of)
Nerve Damage
Nervous Exhaustion
Nervousness
Neurosis
Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
Senility
Shock
Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
Sugar Cravings
Surgery (healing from)
Surgery (preparation for)
Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores
Adrenal Fatigue
Abscesses
Allergies (respiratory)
Abdominal Pain
Acid Indigestion
Cholesterol (high)
Circulation (poor)
Constipation (adults)
Convulsions
Cramps (leg)
Cramps (menstrual)
Cramps and Spasms
Depression
Diabetes
Digestion (poor)
Dizziness
Gastritis
Headache (general)
Heart Fibrillation or Palpitations
Hypertension
Insomnia