Evidence supporting the use of: Curcumin
For the health condition: Canker Sores

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcumin, the primary active component of turmeric (Curcuma longa), has been increasingly studied for its potential role in supporting or treating canker sores (aphthous ulcers). The evidence supporting its use is primarily scientific, with several small-scale clinical trials and in vitro studies indicating beneficial effects. Curcumin exhibits potent anti-inflammatory, antioxidant, and antimicrobial properties, all of which are relevant to the pathophysiology of canker sores, which involve local inflammation and tissue damage.

A number of randomized controlled trials (RCTs), mostly conducted in India and Iran, have evaluated curcumin gel or mouthwash in the management of minor aphthous ulcers. These studies generally report that topical curcumin can significantly reduce pain, erythema, and ulcer size compared to placebo, and in some cases, its efficacy is comparable to standard treatments like corticosteroid gels. For example, a 2014 double-blind study published in the Journal of Oral Pathology & Medicine found that a 2% curcumin gel was as effective as triamcinolone acetonide in decreasing ulcer severity and pain over 7 days.

It should be noted, however, that while these results are promising, most studies are small, and larger, well-designed clinical trials are needed to confirm efficacy and safety. Nonetheless, current scientific evidence supports the potential use of topical curcumin as an adjunct or alternative treatment for canker sores, particularly for individuals seeking non-steroidal options.

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Other ingredients used for Canker Sores

Acacia
Acemannan
Achyranthes
Agastache
Agrimonia pilosa
Agrimony
Aloe vera
American Liverleaf
Amor seco
anamu
Ardisia
Arisaema
ash
aster root
Asteraceae
avens
bacteria
bai ji
balsam
bamboo
banyan
Baphicacanthus cusia
Barleria
basil
Bassia scoparia
bayleaf
bee products
bee propolis
bermuda grass
betel
bicarbonate
Bidens pilosa
bishop\'s weed
bitter grass
black galingale
black nightshade
blackberry
blackboard tree
blackthorn
bloodroot
blue flag
Bombax
Borassus aethiopum
borneol
boxthorne
buckthorn
bасора
cajuput
Calendula
capillary artemisia
capsaicin
carvacrol
Celosia
Centipeda
chamomile
chickweed
Chinese raisintree
chlorophyllin
chrysophanics
Cistus
citron
Clerodendrum indicum
Clerodendrum trichotomum
clove
coconut
coconut milk
Collinsonia
commiphora
copaiba oil
Coptis chinensis
corktree
cowherb
curcumin
curry leaf
David\'s milkberry
Dianthus
divi-divi
dog rose
dragonhead
Eclipta
Embelia
essential oil blend
eucalyptus
eugenol
Euphorbia
Eupolyphaga sinensis
European Elder
European five-finger grass
fang-feng
ferula assafoetida
Ficus simplicissima
Flueggea suffruticosa
folate
frankincense
Fuchsia
Galangal
gallotannin
giant blazingstar
ginger
Glechoma hederacea
Glycolic acid
Gnaphalium
Guava
Guazuma ulmifolia
heal-all
Helicteres isora
henna
Herb Robert
herbal blend (proprietary)
honey
Horsemint
horseradish
Huang hua
hyacinth bean
Indian coraltree
Indian fagonia
Indian kinotree
Indian nightshade
indigo leaves
iridoid glycosides
labrador tea
Lactobacillus reuteri
Lactobacillus salivarius
Lactoperoxidase
Lebbek
Ledebouriella
lemon
lemongrass
Lesser speargrass
licorice root
lime
Litsea
little ironweed
lodhtree
long pepper
luffa
Lysimachia
lysozyme
Macaranga indica
magnesium
mallow
Malva sylvestris
manzanita
marigold
Marjoram
Matapalo Tree
Matico
Melia
Menthol oil
Milk
Mineral ascorbate
Momordica
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Mustard
mustard seed
Myrobalan
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Nimbidin
nut grass
Nutmeg
Oak
omega-3 fatty acids
Onosma bracteatum
oregano
oregon grape
oriental arborvitae
Orris
Osha
Oxystelma
pagoda tree
Pansit-pansitan
papaya
Papayotin
Paris polyphylla
parsley
Patrinia
paw paw
Pentatropis capensis
Pepper
Peppermint
Petiveria
Phyllanthus
Physalis angulata
pineapple
Piper nigrum
Plantago
plantain
Plectranthus amboinicus
Pluchea
Portulaca
Premna
Propolis
Prunus
Pyrrosia
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resin
rhizome
Rhus coriaria
rose
Rubus
rue
sage
Sagebrush
Salvia
Sandalwood
Sanguisorba
Scabrous Gentian
schizonepeta
scrophularia root
Sesbania
sheep's sorrel
Sichuan Lovage
Sicklepod
siler root
Sinapis arvensis
Slippery Elm
slippery elm bark
Smartweed
Snakeroot
Solanum indicum
Sophora
Spanish Needle
Sphaeranthus indicus
Spilanthes
spruce
squawvine
Stereospermum
Sumac
Sweet Bay
Tagetes
Tamaricaceae
Tamarind
Tansy
Terpenoids
thyme
Thymol
Thymus
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Triphala
typhonium
Varuna
Viola
Violet
vitamin B12
vitamin C
Water Pepper
Winter Begonia
Winter Savory
xanthium (cockleburs)
Yellow root
Yellow-Fruit Nightshade
zanthoxylum
Zinc
Zingiberene