Evidence supporting the use of: Magnesium
For the body system: Ovaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Magnesium is an essential mineral that plays a critical role in various physiological processes, including those related to reproductive health. Scientific evidence supports its involvement in the regulation of the hypothalamic-pituitary-ovarian (HPO) axis, which governs ovarian function. Magnesium is a cofactor for enzymes involved in steroidogenesis, the process by which the ovaries produce sex hormones such as estrogen and progesterone. Deficiency in magnesium has been correlated with menstrual irregularities, dysmenorrhea, and symptoms of premenstrual syndrome (PMS), which are all related to ovarian function.

Several clinical studies have investigated magnesium supplementation for PMS and menstrual pain, with some showing benefits such as reduction in pain and improvement in mood symptoms. Additionally, magnesium may help mitigate insulin resistance, a common feature of polycystic ovary syndrome (PCOS), a disorder of ovarian dysfunction. However, while the mineral is important for overall metabolic and reproductive health, direct evidence for magnesium supplementation improving ovarian function or fertility in healthy women is limited.

In summary, magnesium’s use to support the ovaries is scientifically plausible and supported by moderate evidence, particularly in contexts involving menstrual symptoms and metabolic disturbances like PCOS. Further research is needed to clarify its direct effects on ovarian health and function in the general population.

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