Evidence supporting the use of: Polyphenol (unspecified)
For the health condition: Wrinkles
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Polyphenols are a diverse group of naturally occurring compounds found in plants, including fruits, vegetables, tea, and wine. Their use for supporting or treating wrinkles is primarily based on scientific research, although the evidence is still emerging and not robust. Polyphenols possess antioxidant properties, which can help protect the skin from oxidative stress caused by ultraviolet (UV) radiation—a key factor in skin aging and wrinkle formation. In vitro and some animal studies have shown that polyphenols, such as those from green tea (epigallocatechin gallate), grapes (resveratrol), and other sources, can protect against collagen degradation, reduce inflammation, and increase skin hydration and elasticity.
Some small clinical studies have found that topical or oral polyphenol formulations may improve skin texture and reduce the appearance of wrinkles. For example, randomized controlled trials with green tea polyphenol extracts have reported modest improvements in skin elasticity and reduction in wrinkle depth. However, these studies often use specific, standardized extracts rather than "unspecified" polyphenols, and results are not always consistent. Overall, while there is a scientific rationale for the use of polyphenols in skin aging, the clinical evidence—especially for unspecified polyphenols—is limited and not definitive. More large-scale, high-quality human studies are needed to confirm their efficacy for wrinkle reduction.
Other ingredients used for Wrinkles
aloe veraanthocyanins
apricot
ascorbyl palmitate
astaxanthin
beta-carotene
blueberry
collagen
cryptoxanthin
d-alpha tocopherol
gelatin
genistein
grape
green tea
hyaluronic acid
l-carnosine
lycopene
matcha
mixed carotenoids
resveratrol
silicon
almond fruit
Urolithin A
vitamin A
vitamin C
β-nicotinamide mononucleotide (NMN)
neem tree
ferulic acid
Equol (proprietary)
Avocado
Alpha Hydroxy Acids
Alpha-Lipoic Acid
Argan nut oil
Centella triterpenes
Carnosine
Cocoa Butter
Cycloastragenol
Fo-Ti
Flavanones
Flavanols
Flavones
Glycolic acid
Glycosylceramides
Gerovital H3
Glabridin
silica
walnut
Other health conditions supported by Polyphenol (unspecified)
Aging (prevention)Alzheimer's Disease
Arthritis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Diabetes
Diabetic Retinopathy
Digestion (poor)
Fatty Liver Disease
Free Radical Damage
Gastritis
Gingivitis
Hypertension
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Osteoporosis
Psoriasis
Rheumatoid Arthritis
Skin Care (general)
Stress
Triglycerides (high)
Ulcers
Wrinkles