Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phytofluene is a colorless carotenoid found in tomatoes and other fruits and vegetables. Its use in skincare, including for the treatment or prevention of wrinkles, is based on its antioxidant properties and its ability to absorb UV light. Several in vitro and animal studies have shown that phytofluene, along with other carotenoids, can reduce oxidative stress in the skin—an important factor in the development of wrinkles and other signs of aging. By neutralizing free radicals and providing some degree of photoprotection, phytofluene may help slow the breakdown of collagen and elastin in the skin.

However, direct clinical studies examining the effect of phytofluene on wrinkles in humans are limited. Most available research comes from studies of tomato extract or broader carotenoid mixtures, rather than isolated phytofluene. Some small human studies have shown improvements in skin texture and reduced UV-induced damage with carotenoid supplementation, but the effects specific to phytofluene are not well defined. Overall, the scientific evidence supporting its use for wrinkles is suggestive but not conclusive, justifying a moderate evidence rating.

In summary, phytofluene is used in anti-aging skincare primarily due to its antioxidant and photoprotective mechanisms, with limited but promising scientific evidence supporting its role in reducing or preventing wrinkles.

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