Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Hydrolyzed beef collagen is commonly used in dietary supplements marketed for skin health, including the reduction of wrinkles. There is a growing body of scientific evidence suggesting that oral collagen supplementation can have beneficial effects on skin elasticity, hydration, and the appearance of wrinkles. Most studies have focused on hydrolyzed collagen peptides derived from bovine (beef), porcine, or marine sources, with bovine being one of the most prevalent due to its availability and amino acid profile.

Clinical trials, including randomized, placebo-controlled studies, have shown that daily supplementation with hydrolyzed collagen (typically 2.5-10 grams per day for 4-12 weeks) can improve parameters such as skin elasticity, moisture, and wrinkle depth compared to placebo. Proposed mechanisms include stimulation of dermal fibroblast activity and increased production of endogenous collagen, elastin, and hyaluronic acid in the skin. However, while results are promising, many studies are small, funded by manufacturers, and sometimes lack long-term follow-up.

Despite these limitations, the use of hydrolyzed beef collagen for wrinkle reduction is supported by a moderate level of scientific evidence, leading to a rating of 3 out of 5. Further large-scale, independent studies are needed to confirm efficacy and to determine optimal dosing and source specificity. Historical or traditional use of beef collagen for wrinkles is limited; most applications have emerged from recent scientific research and product development.

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