Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Glycolic acid is an alpha hydroxy acid (AHA) commonly used in dermatology and cosmetic products to address wrinkles and other signs of photoaging. Its efficacy is supported by multiple clinical studies and reviews. Glycolic acid works by exfoliating the stratum corneum, promoting desquamation, and increasing epidermal turnover. This process can help to smooth the skin’s surface, reduce fine lines, and improve overall skin texture. Furthermore, glycolic acid has been shown to stimulate collagen production in the dermis, which plays a key role in reducing the appearance of wrinkles.

Clinical evidence includes randomized controlled trials and split-face studies that indicate significant improvements in skin texture, fine lines, and skin elasticity after regular use of glycolic acid peels or topical formulations at concentrations typically ranging from 5% to 70%. The American Academy of Dermatology and several dermatologic review articles endorse glycolic acid as an effective ingredient for anti-aging skincare.

However, while significant improvements in mild to moderate wrinkles have been documented, the effects on deeper wrinkles are less pronounced. Most studies note that consistent, long-term use is necessary to maintain results. Adverse effects, such as irritation and photosensitivity, may occur, so proper use and sun protection are important.

In summary, glycolic acid is scientifically validated as a treatment to support the reduction of wrinkles, with a solid body of evidence supporting its efficacy, particularly for superficial wrinkles and overall skin rejuvenation.

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