Evidence supporting the use of: Flavanols (various)
For the health condition: Wrinkles
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Flavanols, a class of polyphenolic compounds found in foods like cocoa, tea, apples, and berries, have been studied for their potential benefits for skin health, including the reduction of wrinkles. The scientific evidence supporting the use of flavanols for wrinkles is limited but growing. Several small-scale clinical trials, particularly with cocoa flavanols, have demonstrated improvements in skin elasticity, hydration, and density, which are factors related to wrinkle formation. For example, a 2006 randomized controlled trial found that women who consumed high-flavanol cocoa daily for 12 weeks experienced improved skin texture and reduced roughness compared to a low-flavanol group. Other studies have observed increased dermal blood flow and photoprotection from UV-induced damage, both of which may indirectly help prevent wrinkle formation.
Despite these promising findings, the evidence base is not robust. Most studies have small sample sizes and are of short duration. There is also variability in the flavanol content and composition used in different studies, making it difficult to generalize results. While some mechanistic studies suggest that flavanols may exert antioxidant and anti-inflammatory effects that protect collagen and elastin (key proteins in skin structure), more large-scale, long-term trials are needed to confirm real-world benefits for wrinkle reduction. Therefore, while there is initial scientific support for flavanols in improving skin health and potentially reducing wrinkles, the strength of evidence is moderate at best.
Other ingredients used for Wrinkles
aloe veraanthocyanins
apricot
ascorbyl palmitate
astaxanthin
beta-carotene
blueberry
collagen
cryptoxanthin
d-alpha tocopherol
gelatin
genistein
grape
green tea
hyaluronic acid
l-carnosine
lycopene
matcha
mixed carotenoids
resveratrol
silicon
almond fruit
Urolithin A
vitamin A
vitamin C
β-nicotinamide mononucleotide (NMN)
neem tree
ferulic acid
Equol (proprietary)
Avocado
Alpha Hydroxy Acids
Alpha-Lipoic Acid
Argan nut oil
Centella triterpenes
Carnosine
Cocoa Butter
Cycloastragenol
walnut
Other health conditions supported by flavanols (various)
Alzheimer's DiseaseArteriosclerosis
Blood Clots (prevention of)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Circulation (to the brain)
Congestive Heart Failure
Diabetes
Diabetic Retinopathy
Digestion (poor)
Fatigue
Free Radical Damage
Gastritis
Gingivitis
Hypertension
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Osteoporosis
Peripheral Neuropathy
Rheumatoid Arthritis
Skin Care (general)
Stress
Triglycerides (high)
Varicose Veins
Wrinkles