Evidence supporting the use of: Aloe vera
For the health condition: Wrinkles
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Aloe vera has a longstanding history in traditional medicine for skin care, but in recent years, scientific research has begun to explore its effectiveness for supporting or treating wrinkles. Several small-scale studies have investigated aloe vera’s potential anti-aging properties. For instance, research published in the journal Annals of Dermatology (2009) found that oral supplementation with aloe vera gel increased collagen production and improved skin elasticity in women over 45, both of which are factors in wrinkle formation and appearance. Other studies have suggested that topical application of aloe vera may improve skin hydration, stimulate fibroblast activity, and enhance collagen and elastin fiber synthesis, all of which could help reduce the appearance of fine lines and wrinkles.
However, while these findings are promising, the overall quality and size of studies remain limited. Most research involves small participant groups, short durations, and sometimes lacks control groups or blinding. There are also variations in the formulation and concentration of aloe vera used, making it hard to compare results directly. Therefore, while there is some scientific support for aloe vera’s role in wrinkle reduction, it is not robust or conclusive. More large-scale, well-controlled clinical trials are needed to confirm its effectiveness and to establish standardized guidelines for its use in managing wrinkles.
Other ingredients used for Wrinkles
Almond fruitAloe vera
Alpha hydroxy acids
alpha-lipoic acid
anthocyanins
apricot
argan nut oil
ascorbyl palmitate
astaxanthin
avocado
beta-carotene
blueberry
Carnosine
Centella triterpenes
cocoa butter
collagen
cryptoxanthin
cycloastragenol
d-alpha tocopherol
equol (proprietary)
ferulic acid
flavanols
flavanones
flavones
fo-ti
genistein
Gerovital H3
Glabridin
Glycolic acid
Glycosylceramides
grape
green tea
Haematococcus pluvialis
hyaluronic acid
hydroxytyrosol
Idebenone
jojoba oil
L-carnosine
lycopene
Matcha
mixed carotenoids
Mulberroside A
Neem tree
Phytoene
Phytofluene
polymethoxylated flavones
procyanidin
procyanidol
resveratrol
silica
silicon
Urolithin A
Ursolic Acid
vitamin A
vitamin C
Walnut
β-nicotinamide mononucleotide (NMN)
Other health conditions supported by Aloe vera
AbrasionsAcid Indigestion
Acne
Age Spots
Anal Fistula or Fissure
Athlete's Foot
Bites and Stings
Bleeding (external)
Blisters
Boils
Burns and Scalds
Cancer Treatment (reducing side effects)
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cold Sores
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colitis
Colon (atonic)
Colon (spastic)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Constipation (adults)
Constipation (children)
Convalescence
Corns
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cradle Cap
Crohn's Disease
Cuts
Cysts
Dandruff
Denture Sores
Dermatitis
Diabetes
Diaper Rash
Digestion (poor)
Duodenal Ulcers
Dysentery
Dyspepsia
Eczema
Enteritis
Foot Odor
Fungal Infections
Gastritis
Gingivitis
Halitosis
Hemorrhoids
Hiatal Hernia
Indigestion
Inflammatory Bowel Disorders
Interstitial Cystitis
Irritable Bowel Syndrome
Itching
Itching (rectal)
Itching Ears
Jock Itch
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Oral Surgery
Overacidity
Poison Ivy or Oak
Psoriasis
Rashes and Hives
Rosacea
Scabies
Scars / Scar Tissue
Scratches and Abrasions
Seborrhea
Shingles
Skin (dry and/or flaky)
Skin (infections)
Skin (oily)
Skin Care (general)
Slivers
Sore or Geographic Tongue
Sore Throat
Staph Infections
Stretch Marks
Stye
Sunburn
Surgery (healing from)
Thrush
Tickle in Throat
Tonsillitis
Tooth Extraction
Toothache
Ulcerations (external)
Ulcers
Urethritis
Urinary Tract Infections
Urination (burning or painful)
Urine (scant)
Vaginal Dryness
Vaginitis
Warts
Wounds and Sores
Wrinkles
Abdominal Pain
Abscesses
Inflammation
Injuries
Arthritis
Fever
Herpes
Jaundice (adults)
Liver Detoxification
Menopause
Carbuncles
Cancer (natural therapy for)
