Evidence supporting the use of: Motherwort
For the health condition: Worry

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Motherwort (Leonurus cardiaca) has traditionally been used in Western herbal medicine as a remedy for conditions related to nervousness, anxiety, and emotional distress, which are often collectively referred to as "worry." Historical records trace its use back to ancient Greece, where it was administered to pregnant women for calming effects, and throughout the Middle Ages, it was recommended by herbalists for "melancholy" and agitation. The plant contains various bioactive compounds, including leonurine, which is thought to exert mild sedative effects on the nervous system.

Despite its enduring use in folk medicine, scientific evidence supporting motherwort’s effectiveness for anxiety or worry is limited. Most available information comes from traditional herbal texts and anecdotal reports rather than clinical trials. A handful of animal studies suggest that extracts of motherwort may have anxiolytic (anxiety-reducing) and sedative properties, but well-designed human studies are lacking. Modern herbalists sometimes recommend it as part of blends for emotional support, especially for individuals experiencing stress in conjunction with heart palpitations (its other traditional indication).

In summary, the use of motherwort for "worry" is primarily justified by tradition, and while there is some suggestive preclinical evidence, robust scientific validation is lacking. Individuals interested in trying motherwort for anxiety or worry should consult with a healthcare practitioner, particularly if they are taking medications or have underlying health conditions.

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