Evidence supporting the use of: Cordyceps
For the health condition: Wasting

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cordyceps, particularly Cordyceps sinensis and Cordyceps militaris, has a long history of use in traditional Chinese medicine (TCM) for treating fatigue, weakness, and conditions associated with wasting, such as chronic illness and aging. In TCM, it is believed to tonify the kidney and lung, boost energy, and improve stamina. Modern scientific investigation has begun to explore these traditional claims, and there is some preliminary evidence suggesting that cordyceps may have benefits relevant to wasting conditions (often characterized by muscle loss, fatigue, and diminished physical function, as seen in cachexia or chronic illness).

Several animal studies have indicated that cordyceps extracts can help improve endurance, reduce fatigue, and possibly mitigate muscle atrophy. The mechanisms proposed include enhanced ATP production, improved oxygen utilization, anti-inflammatory effects, and modulation of immune function. Small-scale clinical trials have shown improvements in exercise performance and fatigue in elderly individuals or patients with chronic illnesses, though these studies are generally limited by small sample sizes and methodological weaknesses.

Overall, while traditional use is strong and there is a growing body of preclinical evidence, robust clinical trials are lacking. The current scientific support is modest (rated 2/5), indicating that cordyceps shows promise for supporting conditions involving wasting, but more high-quality research is needed to confirm its efficacy and establish standardized treatment protocols.

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