Evidence supporting the use of: Lactobacillus salivarius
For the health condition: Vaginitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus salivarius is a probiotic species that has been investigated for its role in supporting vaginal health and treating vaginitis. The primary rationale for its use is based on the understanding that the healthy vaginal microbiome is dominated by Lactobacillus species, which help maintain an acidic environment (low pH) and produce antimicrobial substances (e.g., lactic acid, hydrogen peroxide) that inhibit the growth of pathogenic organisms commonly associated with vaginitis, such as Gardnerella vaginalis and Candida albicans.

Several clinical studies and in vitro experiments have shown that certain strains of L. salivarius can adhere to vaginal epithelial cells, outcompete harmful microbes, and restore healthy vaginal flora after disturbances (such as antibiotic use or infection). For example, a 2018 randomized controlled trial found that a probiotic supplement containing L. salivarius improved symptoms and reduced recurrence rates in women with bacterial vaginosis. Other studies have demonstrated immunomodulatory and anti-inflammatory effects relevant to vaginitis treatment. However, while the evidence is promising, it is still emerging: most studies have small sample sizes and use multi-strain probiotic formulations, making it difficult to isolate the effects of L. salivarius alone.

Overall, the use of L. salivarius for vaginitis is scientifically supported, though the evidence is moderate (rated 3/5) and more large-scale, strain-specific clinical trials are needed to fully validate its efficacy and determine optimal strains and dosages.

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