Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus gasseri is a species of probiotic bacteria that naturally colonizes the vaginal microbiota and is recognized for its potential role in the prevention and management of vaginitis, particularly bacterial vaginosis (BV) and vulvovaginal candidiasis. Scientific studies have indicated that L. gasseri can inhibit the growth of pathogenic microorganisms through mechanisms such as the production of lactic acid, hydrogen peroxide, and bacteriocins, which help maintain an acidic vaginal pH and suppress harmful bacteria and yeast.

Clinical trials and in vitro studies have shown that supplementation with L. gasseri (alone or in combination with other lactobacilli) can help restore healthy vaginal flora, especially after antibiotic treatment, and may reduce recurrent episodes of vaginitis. For example, a 2014 randomized controlled trial demonstrated that intravaginal administration of L. gasseri improved symptoms and reduced recurrence in women with bacterial vaginosis compared to placebo. However, the quality and quantity of evidence are still limited, and most studies to date have involved small sample sizes or used mixed probiotic formulations.

Overall, the use of L. gasseri for vaginitis is supported by a moderate body of scientific evidence, though more large-scale and well-designed clinical trials are needed to confirm its efficacy and determine optimal dosing and delivery methods. Nevertheless, it is increasingly recognized as a beneficial adjunct in the management of vaginal infections, especially for those seeking non-antibiotic preventive strategies.

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