Evidence supporting the use of: Lactobacillus salivarius
For the body system: Vagina

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus salivarius is a probiotic bacterium that has been studied for its role in supporting vaginal health. Scientific evidence suggests that L. salivarius can contribute to the maintenance of a healthy vaginal microbiota, although it is less extensively studied than other lactobacilli, such as L. crispatus or L. rhamnosus. Several in vitro and in vivo studies have indicated that L. salivarius is capable of producing lactic acid and bacteriocins, substances that help lower vaginal pH and inhibit the growth of pathogenic organisms, including Candida species and Gardnerella vaginalis.

Clinical studies are limited but promising. A few small trials and observational studies have demonstrated that oral or vaginal administration of L. salivarius can help restore the balance of vaginal flora in women with bacterial vaginosis or recurrent vaginal infections. For example, a 2014 pilot study found that L. salivarius CECT5713 supplementation was associated with improved vaginal microbial profiles and symptom relief in women with vaginal dysbiosis.

Despite these positive findings, more robust clinical trials are necessary to fully establish efficacy, optimal dosing, and safety. Overall, its use is supported by preliminary scientific evidence, but not as conclusively as some other lactobacilli. Therefore, the evidence rating is moderate (3/5).

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