Evidence supporting the use of: Lactobacillus acidophilus
For the body system: Vagina

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Lactobacillus acidophilus is one of the most extensively studied probiotic species for supporting vaginal health. The scientific rationale is based on the fact that a healthy vaginal microbiome is typically dominated by Lactobacillus species, which help to maintain an acidic environment (low pH) through the production of lactic acid. This acidic environment inhibits the growth of pathogenic bacteria and yeast, such as Gardnerella vaginalis (associated with bacterial vaginosis) and Candida albicans (associated with yeast infections).

Several clinical studies have demonstrated that oral or intravaginal administration of L. acidophilus can help restore normal vaginal flora and reduce the recurrence of both bacterial vaginosis and vulvovaginal candidiasis, especially when used alongside standard antimicrobial therapies. For example, a 2014 meta-analysis (Huang et al., 2014) found that probiotic supplementation, including L. acidophilus, significantly improved cure rates of bacterial vaginosis compared to placebo.

However, while the evidence is strong for some strains and formulations, results can vary, and not all studies show benefit. The greatest support is for multi-strain Lactobacillus probiotics and use as an adjunct to antibiotics or antifungals. Still, the use of L. acidophilus for vaginal health is grounded in modern scientific research rather than just tradition.

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