Evidence supporting the use of: Isoflavones
For the body system: Vagina

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Isoflavones, particularly those derived from soy, are phytoestrogens—plant compounds with a structure similar to human estrogen. Their use in supporting the vaginal body system, especially in postmenopausal women, is based on their ability to weakly bind to estrogen receptors and exert mild estrogen-like effects. This is relevant because estrogen plays a crucial role in maintaining vaginal tissue health; after menopause, decreased estrogen levels often lead to symptoms such as vaginal dryness, atrophy, and discomfort.

Several clinical trials and systematic reviews have evaluated the efficacy of isoflavones for alleviating these symptoms. Some randomized controlled trials have reported that soy isoflavone supplementation can improve vaginal cytology and reduce dryness, though the effects are generally modest and not universally observed. A 2016 meta-analysis published in Maturitas found that phytoestrogens, including isoflavones, may offer some benefit for vaginal atrophy, but highlighted considerable variability between studies and called for further high-quality research.

Overall, the use of isoflavones for vaginal health is supported by a plausible mechanism and some clinical data, but evidence is not robust or consistent enough to warrant a higher rating. Isoflavones are not a standard therapy and should not replace established treatments for vaginal atrophy, but they may be considered as an adjunct or alternative for women seeking non-hormonal options.

More about Isoflavones
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Products containing Isoflavones

We currently have no products on Caring Sunshine that contain this ingredient.