Evidence supporting the use of: Diosgenin
For the body system: Uterus
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Diosgenin is a naturally occurring steroidal sapogenin found in various plants, most notably wild yam (Dioscorea species). Traditionally, diosgenin-containing plants have been used in folk medicine to support women's reproductive health, including uterine function, menstrual regularity, and menopausal symptoms. These uses are particularly common in traditional Chinese medicine and Native American herbalism. The rationale behind its traditional use is based on the fact that diosgenin is a precursor for the laboratory synthesis of steroid hormones such as progesterone and estrogen. However, in the human body, diosgenin itself is not converted into these hormones naturally; this transformation requires industrial chemical processes.
Scientific research on diosgenin's direct effect on the uterus is limited. Some in vitro and animal studies suggest that diosgenin may exhibit weak estrogenic or anti-inflammatory activity, which could theoretically influence uterine health. However, these effects have not been conclusively demonstrated in human clinical trials. The bulk of evidence supporting diosgenin for uterine health remains anecdotal or based on traditional practices rather than robust scientific validation. Therefore, while there is a traditional basis for using diosgenin to support the uterus, modern scientific evidence is insufficient to strongly endorse its efficacy for this purpose.
Other ingredients that support Uterus
astragalusblack cohosh
chamomile
chaste tree
damiana
dong quai root
fennel
fenugreek
folate
genistein
ginger
ginseng
gotu kola
licorice root
lignans
maca
magnesium
motherwort
parsley
protein
raspberry
rose oil
wild yam
zinc
red clover
squawvine
chickweed
mugwort
anise
blessed thistle
peony
yarrow
root tuber
dioscorea
guelder rose
shepherd's purse
soy isoflavones
Angelica
Alchemilla
Aletris
Anserina
Agnuside
Ashoka
Abuta
Blue Cohosh
Bugbane
Bethroot
Barbasco
Cohosh
Clary sage
Cramp Bark
Casticin
Crinum latifolium
Carthamus
Daidzein
Dong Quai
Diosgenin
Evening Primrose Oil
Estrogen
Folic Acid
Fo-Ti
False Unicorn Root
Giant Trillium
Golden Ragwort
Isoflavones
jasmine
Pennyroyal
Rose
Other body systems supported by Diosgenin
EstrogenFemale Reproductive System
Glandular System
Reproductive System
Uterus