Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lophatherum leaf (Lophatherum gracile), known as "Danzhuye" in traditional Chinese medicine (TCM), is primarily used based on traditional practices to support or treat urinary tract infections (UTIs) and related symptoms such as dysuria (painful urination), scanty urine, or urinary heat. In TCM, Lophatherum leaf is considered to have "heat-clearing" and "dampness-draining" properties, which are thought to help eliminate pathogenic heat from the heart and small intestine channels, thereby benefiting conditions with urinary discomfort.

Several classical TCM texts mention Danzhuye as an ingredient in formulas for treating urinary problems, fever, and mouth sores. However, the scientific evidence supporting these uses is limited. Some in vitro and animal studies have reported mild anti-inflammatory and diuretic effects of Lophatherum gracile extracts, which could theoretically be beneficial in managing certain urinary symptoms. These experimental results, however, are preliminary and not specific to UTIs, and there are no robust clinical trials in humans confirming its effectiveness for this indication.

Overall, the use of Lophatherum leaf for urinary tract infections is rooted in tradition, with low-quality supporting evidence from modern scientific research. Its application is largely based on its historical use in herbal medicine rather than validated clinical efficacy.

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