Euphorbia pekinensis (commonly known as "Peking Spurge" or "Lu Lu Tong" in traditional Chinese medicine) has a long history of use in East Asian herbal practices. Traditionally, the root of Euphorbia pekinensis is used as a harsh purgative and diuretic, and is incorporated into classical Chinese herbal formulas for its perceived abilities to "expel water," reduce edema, and relieve urinary retention. This diuretic effect is the basis of its occasional inclusion in traditional remedies for urinary tract issues, including difficulty in urination or possibly urinary tract infections (UTIs). However, its main use is typically for severe fluid retention and constipation rather than for infectious processes.

There is little to no direct scientific evidence supporting the use of Euphorbia pekinensis specifically for the treatment or support of urinary tract infections. Modern pharmacological studies on this plant focus primarily on its purgative, cytotoxic, or anti-inflammatory properties, with some research noting potential toxicity. There is no substantial evidence from clinical trials or pharmacological studies validating its efficacy or safety for UTIs. As such, its use for urinary tract infections is based on traditional practice rather than modern scientific validation, and the evidence supporting its effectiveness for this indication is weak.