Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Alisma (Alisma orientale or Alisma plantago-aquatica), known as "ze xie" in traditional Chinese medicine (TCM), has a longstanding use in East Asian herbal practice, particularly for promoting urination, resolving dampness, and supporting urinary tract health. Historical TCM texts describe Alisma as beneficial for conditions characterized by "damp-heat" in the lower burner, which may correspond to symptoms associated with urinary tract infections (UTIs), such as difficult urination, swelling, or urinary discomfort. The herb is commonly included in classical formulas aimed at clearing dampness and supporting bladder function.

Modern scientific evidence for Alisma’s efficacy in treating UTIs specifically is limited. Some in vitro and animal studies suggest that extracts of Alisma may have mild anti-inflammatory and diuretic effects, which could theoretically support urinary tract health. However, robust clinical trials in humans are lacking, and no direct evidence supports its effectiveness against the bacterial pathogens responsible for most UTIs. Thus, while Alisma is traditionally used for urinary symptoms and as a mild diuretic, the strength of evidence remains low, and it should not replace standard antibiotic therapy where indicated.

In summary, the use of Alisma to support or treat urinary tract infections is primarily justified by traditional practice, with some weak supporting evidence from pharmacological studies, but no strong scientific validation at this time.

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