Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The Rubiaceae family is a large plant family that includes numerous genera and species, such as Coffea (coffee), Cinchona (source of quinine), Gardenia, and Morinda (noni). Several traditional medicinal systems have used various Rubiaceae species for urinary system support. For example, Morinda citrifolia (noni) fruits and roots have been used in Polynesian and Southeast Asian folk medicine as diuretics and for the treatment of urinary tract infections and kidney-related issues. Similarly, some species of Oldenlandia (e.g., Oldenlandia diffusa) are used in Traditional Chinese Medicine for their purported anti-inflammatory and diuretic properties. However, most of these uses are based on traditional knowledge rather than robust scientific validation. While some in vitro and animal studies suggest diuretic or anti-inflammatory effects for extracts from these plants, there is limited high-quality clinical evidence supporting their efficacy for urinary system health in humans. In summary, the use of unspecified Rubiaceae for urinary system support is primarily rooted in traditional practices, with only modest preliminary scientific investigation and little to no conclusive clinical evidence.

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