Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Stachytarpheta cayennensis, commonly known as blue snakeweed or Cayenne snakeweed, has been traditionally used in various cultures for the treatment of ulcers, particularly gastric ulcers. Ethnobotanical surveys from regions such as the Caribbean, West Africa, and parts of Central and South America document its use in folk medicine for managing peptic ulcers, as well as for general gastrointestinal complaints. The plant is often prepared as a decoction or infusion, and sometimes as a poultice applied externally to ulcerated wounds. The traditional justification for its use is largely anecdotal, passed down through generations, and is rooted in its perceived anti-inflammatory and soothing properties. Scientifically, there is limited evidence directly supporting the efficacy of Stachytarpheta cayennensis for ulcer treatment. Some preliminary in vivo studies and phytochemical analyses have identified the presence of flavonoids, saponins, and other compounds with potential anti-ulcer or gastroprotective activities. However, these studies are few, often conducted on animal models, and do not provide robust clinical validation. No high-quality, peer-reviewed human clinical trials have confirmed its effectiveness or safety for ulcer management. Therefore, while traditional use is well-documented, scientific support remains weak, leading to a modest evidence rating of 2 out of 5.

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