Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Cinidium (commonly referring to Cnidium monnieri, also known as She Chuang Zi in traditional Chinese medicine) has a long-standing history of use in East Asian herbal medicine. Its seeds have been traditionally utilized for various ailments, primarily related to skin disorders, sexual health, and as a general tonic. In the context of ulcers—especially gastrointestinal ulcers—there is some traditional rationale for its use. Classical Chinese medicinal texts occasionally mention Cnidium in formulations aimed at wound healing or gastrointestinal comfort, based on its perceived properties to "remove dampness" and "promote healing."

However, the direct use of Cinidium/Cnidium for treating gastric or peptic ulcers is not one of its most prominent historical indications. There is limited preclinical evidence that some constituents of Cnidium, such as osthole, possess anti-inflammatory and antioxidant activity, which could theoretically contribute to mucosal protection. Nevertheless, robust scientific studies specifically demonstrating efficacy for ulcer healing or prevention are lacking. The evidence is therefore primarily traditional, with only low-level support from laboratory studies and no high-quality clinical trials confirming effectiveness for ulcer treatment. In summary, the use of Cinidium for ulcers is based more on traditional practices and theoretical mechanisms than on strong scientific evidence.

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