Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Trichoderma viride is primarily supported by traditional evidence for the treatment or support of external ulcerations. In traditional medicine systems, particularly in some regions of India, preparations made from Trichoderma viride are used topically for their purported antimicrobial and wound-healing properties. Ethnobotanical surveys and Ayurvedic texts occasionally mention the use of this fungus (or its preparations) as a folk remedy for skin conditions such as ulcers, wounds, and infections, citing its observed ability to inhibit the growth of pathogenic microbes.

However, direct scientific validation for its clinical use in treating external ulcerations in humans is limited. A small number of laboratory studies have demonstrated that Trichoderma viride produces secondary metabolites with antibacterial and antifungal properties, which could theoretically benefit wound healing and infection control. Yet, these findings are largely preclinical and have not been translated into robust clinical trials or standardized medical practice. There is a lack of peer-reviewed clinical studies directly assessing the efficacy or safety of Trichoderma viride preparations in the treatment of human ulcerations.

In summary, the use of Trichoderma viride for external ulcerations is mostly based on traditional or folk medicinal practices, with some laboratory evidence suggesting a plausible mechanism of action but insufficient clinical data to fully validate its effectiveness or safety.

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