Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Tannins, a diverse group of polyphenolic compounds found in various plants, have traditionally been used to support the healing of external ulcerations and wounds. Their astringent properties are well-documented in herbal medicine systems across the globe, including in European, Chinese, and Ayurvedic traditions. When applied topically, tannins cause precipitation of proteins on the superficial layers of the skin and mucous membranes, forming a protective barrier that can reduce irritation and support the healing process. This also helps to limit exudation and can create an environment less conducive to microbial growth.

While there are a few in vitro and animal studies indicating antimicrobial and wound-healing properties of tannin-rich plant extracts, clinical studies in humans are limited and often focus on specific plant sources rather than purified or mixed tannins. As such, their use for external ulcerations is primarily grounded in traditional knowledge rather than robust scientific validation. Nonetheless, the astringency and local antimicrobial effects observed in laboratory settings provide some mechanistic rationale for their topical use. Overall, tannins’ role in supporting external ulcerations is considered traditional with modest evidence (rated 2) and should be used with caution, considering possible skin irritation or allergic reactions.

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