Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sapindus mukorossi, commonly known as soapnut or reetha, has been traditionally used in various Ayurvedic and folk medicine practices, including for the treatment of external ulcerations. Historical texts and ethnobotanical surveys reference the use of Sapindus mukorossi fruit pericarp extracts in poultices, washes, or pastes applied to wounds, ulcers, or skin eruptions. The rationale for its use is partly due to its saponin content, which imparts cleansing and mild antimicrobial effects believed to aid in wound cleaning and the prevention of secondary infections.

However, the scientific evidence supporting this use remains limited. While some in vitro studies have demonstrated that Sapindus saponins possess antibacterial and anti-inflammatory properties, there is a lack of well-designed clinical or animal studies directly evaluating its efficacy in promoting the healing of ulcers or wounds in vivo. The majority of references to its application for ulcerations are found in compilations of traditional knowledge rather than in peer-reviewed pharmacological research.

In summary, the use of Sapindus mukorossi for external ulcerations is primarily justified by traditional practices, with only limited pharmacological data supporting its potential mechanisms and virtually no robust clinical validation. Its evidence rating is therefore modest, reflecting a need for more rigorous scientific evaluation.

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