Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mucins are large glycoproteins that are a key component of mucus, providing lubrication and protection to epithelial surfaces. The traditional use of mucins or mucin-containing preparations for the treatment of external ulcerations dates back to various historical medical systems, where natural mucus or mucin-rich substances (such as from snails or animal tissues) were topically applied to wounds and ulcers to promote healing and protect against infection. The rationale was that mucins could form a protective barrier, maintain moisture, and possibly aid the natural healing process. However, while the basic wound-protective properties of mucus are well understood, there is only limited scientific research directly supporting the topical application of purified mucins for treating external ulcerations in humans. Some modern wound dressings aim to mimic mucin-like properties (e.g., by maintaining a moist environment), but purified mucins themselves are not widely used nor well-studied in contemporary clinical practice. Therefore, the evidence supporting their use is mostly traditional and based on historical rather than modern scientific validation. Further research would be needed to clarify their specific benefits and mechanisms in wound healing.

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