Chiococca alba, commonly known as David's milkberry or West Indian milkberry, has a long history of traditional use in Caribbean, Central American, and South American herbal medicine. Its roots and leaves have been applied externally for a variety of skin conditions, including ulcerations, wounds, and sores. Ethnobotanical surveys from regions such as Cuba, Jamaica, and Mexico document its use by local healers and Indigenous practitioners to promote wound healing and treat skin ulcers. The traditional preparation often involves making a poultice or decoction from the root, which is then applied directly to the affected area.

However, scientific validation for these uses is limited. While some laboratory studies have demonstrated that extracts from Chiococca alba possess antimicrobial and antioxidant properties—factors that could theoretically support wound healing—there is a lack of robust clinical trials or in vivo studies specifically investigating its effectiveness for external ulcerations in humans. The available evidence thus remains largely anecdotal and based on traditional medical practices rather than rigorous scientific evaluation.

In summary, the use of Chiococca alba for external ulcerations is primarily justified by traditional knowledge rather than scientific proof, and its efficacy for this purpose should be considered unproven in the context of modern evidence-based medicine.