Evidence supporting the use of: Aloe vera
For the health condition: Ulcerations (external)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Aloe vera has a long history of traditional use for treating external ulcerations, such as skin ulcers, burns, and wounds. Modern scientific research has provided moderate support for its efficacy in this area. The inner gel of Aloe vera contains bioactive compounds, including polysaccharides (notably acemannan), glycoproteins, vitamins, and minerals, which are believed to promote wound healing and exhibit anti-inflammatory, antimicrobial, and immunomodulatory effects. Several in vitro and in vivo studies have demonstrated that Aloe vera can accelerate the healing of skin ulcers by stimulating fibroblast activity, enhancing collagen synthesis, increasing angiogenesis, and reducing inflammation. Clinical trials in humans are somewhat limited but promising; some studies have found that topical application of Aloe vera gel or extracts can improve healing rates and reduce pain in patients with pressure ulcers, diabetic ulcers, and other chronic wounds compared to standard care or placebo. However, not all studies have shown significant benefits, and methodological differences make direct comparisons challenging. Overall, while Aloe vera is widely used and generally considered safe for external application on ulcerations, further high-quality clinical trials are needed to fully establish its efficacy and optimal usage protocols. Nonetheless, the current evidence base supports its use as an adjunct to conventional wound care, justifying a moderate rating for scientific validation.

More about aloe vera
More about Ulcerations (external)

Other health conditions supported by aloe vera

Abdominal Pain
Abrasions
Abscesses
Acid Indigestion
Acne
Age Spots
Anal Fistula or Fissure
Arthritis
Athlete's Foot
Bites and Stings
Bleeding (external)
Blisters
Boils
Burns and Scalds
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Chemotherapy (reducing side effects)
Chicken Pox
Cold Sores
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colitis
Colon (atonic)
Colon (spastic)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Constipation (adults)
Constipation (children)
Convalescence
Corns
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cradle Cap
Crohn's Disease
Cuts
Cysts
Dandruff
Denture Sores
Dermatitis
Diabetes
Diaper Rash
Digestion (poor)
Duodenal Ulcers
Dysentery
Dyspepsia
Eczema
Enteritis
Fever
Foot Odor
Fungal Infections
Gastritis
Gingivitis
Halitosis
Hemorrhoids
Herpes
Hiatal Hernia
Indigestion
Inflammation
Inflammatory Bowel Disorders
Injuries
Interstitial Cystitis
Irritable Bowel Syndrome
Itching
Itching (rectal)
Itching Ears
Jaundice (adults)
Jock Itch
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Liver Detoxification
Menopause
Oral Surgery
Overacidity
Poison Ivy or Oak
Psoriasis
Rashes and Hives
Rosacea
Scabies
Scars / Scar Tissue
Scratches and Abrasions
Seborrhea
Shingles
Skin (dry and/or flaky)
Skin (infections)
Skin (oily)
Skin Care (general)
Slivers
Sore or Geographic Tongue
Sore Throat
Staph Infections
Stretch Marks
Stye
Sunburn
Surgery (healing from)
Thrush
Tickle in Throat
Tonsillitis
Tooth Extraction
Toothache
Ulcerations (external)
Ulcers
Urethritis
Urinary Tract Infections
Urination (burning or painful)
Urine (scant)
Vaginal Dryness
Vaginitis
Warts
Wounds and Sores
Wrinkles