Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Abrus, most commonly referring to Abrus precatorius (commonly known as jequirity or rosary pea), has a history of traditional use in various medical systems, including Ayurveda and folk medicine, for the treatment of external ulcerations. Traditionally, preparations from the leaves, seeds (after detoxification), or roots have been applied topically to wounds, ulcers, and other skin lesions. The rationale for its use in traditional medicine stems from its purported anti-inflammatory, antimicrobial, and wound-healing properties as recorded in classical texts and ethnobotanical reports.

However, there is limited scientific evidence supporting these traditional claims. Few laboratory studies have evaluated Abrus extracts for wound healing, with some reporting moderate antimicrobial activity and possible enhancement of wound closure in animal models. These studies are generally preliminary, use crude extracts, and rarely translate directly to human clinical practice, especially given the toxicity of certain components such as abrin in the seeds. The evidence from modern pharmacological research is insufficient to provide robust support for its use in ulceration, and safety concerns are significant.

Overall, the use of Abrus for external ulcerations is primarily justified by tradition rather than scientific validation, and should be approached with caution due to its potential toxicity.

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