Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Fritillaria species, particularly Fritillaria cirrhosa and Fritillaria thunbergii, have a long history of use in Traditional Chinese Medicine (TCM) for respiratory ailments. In classical TCM texts, Fritillaria bulbs (known as "Chuan Bei Mu" or "Zhe Bei Mu") are prescribed to "clear heat," "transform phlegm," and relieve cough, including chronic coughs that might be associated with tuberculosis (TB). The use of Fritillaria in the context of TB is thus grounded in traditional practice rather than direct scientific validation. Historical records suggest that these bulbs were used to support lung health and alleviate symptoms such as persistent cough, a hallmark of pulmonary TB. However, there is limited modern scientific evidence specifically validating the efficacy of Fritillaria for tuberculosis. While some laboratory and animal studies have identified expectorant, anti-inflammatory, and possibly mild antimicrobial properties in Fritillaria extracts, these do not directly translate to clinical efficacy against Mycobacterium tuberculosis. No high-quality clinical trials have demonstrated that Fritillaria can treat or cure TB in humans. Thus, its traditional use for TB-related symptoms persists in some herbal practices, but this use is not supported by robust scientific evidence, and it should not be relied upon as a primary therapy for tuberculosis, which requires standard antibiotic treatment.

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