Evidence supporting the use of: Cordyceps
For the health condition: Tuberculosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Cordyceps has a longstanding history in traditional Chinese and Tibetan medicine, where it has been used as a general tonic and to support lung health, including for respiratory conditions such as tuberculosis (TB). Historical texts and ethnobotanical reports indicate that Cordyceps species (especially Cordyceps sinensis) were administered to patients with chronic cough, weakness, and to promote recovery after illness, including TB. The rationale in traditional medicine was based on Cordyceps’ perceived ability to "nourish the lungs and kidneys" and "restore vitality." However, this use is grounded in traditional practice rather than rigorous clinical evidence.

From a scientific perspective, there are preclinical studies demonstrating that extracts of Cordyceps possess immunomodulatory, anti-inflammatory, and possibly antimicrobial properties. A small number of laboratory and animal studies have suggested that Cordyceps polysaccharides can stimulate immune responses or inhibit certain pathogens. However, there are no robust clinical trials or substantial scientific evidence directly supporting the use of Cordyceps for the treatment or adjunctive management of active tuberculosis in humans. Thus, while tradition supports its use, the current scientific evidence is minimal and does not justify Cordyceps as a primary or adjunctive therapy for TB outside of traditional contexts.

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