Evidence supporting the use of: Soybean
For the health condition: Triglycerides (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Soybean and soybean-derived products have been investigated for their effects on lipid profiles, including triglyceride levels. Several clinical studies and meta-analyses support the use of soy protein as a modest but significant means of improving blood lipid parameters. The mechanism is thought to be primarily due to the protein content in soy, which may influence hepatic lipid metabolism, as well as the presence of isoflavones and polyunsaturated fatty acids. A 2015 meta-analysis of randomized controlled trials published in the journal Clinical Nutrition found that soy protein supplementation led to a small but significant reduction in serum triglycerides compared to placebo. Another 2011 meta-analysis in European Journal of Clinical Nutrition also reported favorable effects on triglycerides when soy protein replaced animal protein in the diet. The US Food and Drug Administration (FDA) even allows a health claim for soy protein and heart health, which is related to lowering blood cholesterol and, to some extent, triglycerides. However, the degree of triglyceride reduction is generally moderate and soy should be considered part of an overall dietary approach rather than a stand-alone therapy for hypertriglyceridemia. Overall, the evidence supporting the use of soybean for triglyceride reduction is scientific and lies in the moderate range.

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