Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Satsuma mandarin (Citrus unshiu) has been investigated in a limited number of scientific studies for its potential effects on lipid metabolism, including triglycerides. The fruit contains various bioactive compounds, particularly flavonoids such as hesperidin and nobiletin, which have been associated with lipid-lowering effects in preclinical research. Animal studies have demonstrated that extracts from Satsuma mandarin peel or juice can reduce serum triglyceride levels, likely due to their influence on lipid metabolism enzymes and antioxidant properties. For example, a study published in the Journal of Nutritional Science and Vitaminology (2004) found that Citrus unshiu peel extracts lowered triglycerides in rats fed a high-fat diet. In addition, some in vitro studies suggest mechanisms related to improvement in lipid metabolism and reduction in fat accumulation.

However, robust clinical evidence in humans is lacking. Only a few small-scale human studies and trials using related citrus species suggest potential benefits, but these are not sufficient to draw firm conclusions or recommend Satsuma mandarin as a treatment for high triglycerides. There is also no widespread traditional use specifically for hypertriglyceridemia, although citrus fruits in general have been used for various health-promoting purposes in traditional medicine. Overall, while early research is promising, the current evidence supporting the use of Satsuma mandarin for high triglycerides remains preliminary and limited, justifying a low evidence rating.

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