Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Nannochloropsis is a genus of microalgae known for its high content of eicosapentaenoic acid (EPA), an omega-3 polyunsaturated fatty acid. Several scientific studies have investigated the potential of Nannochloropsis-derived oils to modulate blood lipid profiles, including triglyceride levels. The primary mechanism proposed is the reduction of hepatic triglyceride synthesis and increased clearance, similar to the effects seen with fish oil-derived EPA. A randomized controlled trial published in Algal Research (2018) demonstrated that supplementation with Nannochloropsis gaditana oil (providing approximately 250 mg EPA/day) led to significant reductions in serum triglycerides in mildly hypertriglyceridemic adults, compared to placebo. Additional in vitro and animal studies have also shown that Nannochloropsis oil can reduce triglyceride accumulation and improve lipid metabolism.

However, while the evidence is promising, the number of high-quality human trials remains limited, and most studies use relatively modest doses over short durations. The triglyceride-lowering effect appears comparable, though generally less pronounced, than that observed with higher-dose fish oil supplements. Overall, there is moderate scientific validation for the use of Nannochloropsis to help lower elevated triglycerides, especially as a plant-based alternative to fish oil, but more robust clinical trials are needed to confirm its efficacy and optimal dosing.

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