Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Fish liver oil, such as cod liver oil, is used to support the reduction of high triglycerides, and this use is supported by scientific evidence. Fish liver oil contains significant amounts of omega-3 fatty acids (primarily EPA and DHA), which have been extensively studied for their lipid-lowering effects. Multiple randomized controlled trials and meta-analyses have demonstrated that supplementation with omega-3 fatty acids can significantly reduce serum triglyceride levels in individuals with hypertriglyceridemia. The mechanism involves decreased hepatic synthesis of triglycerides and increased clearance from the bloodstream. While most studies focus on fish oil in general (which may be derived from fish body or liver), cod liver oil specifically also provides EPA and DHA in meaningful amounts.

Notably, the American Heart Association and other medical organizations recommend omega-3 supplementation as an adjunct therapy for patients with persistently high triglycerides. The evidence rating is not the maximum because most large-scale trials have tested concentrated omega-3 ethyl esters or fish body oil rather than fish liver oil specifically. Additionally, cod liver oil contains vitamins A and D, which can be toxic at high doses, so it is not always the preferred omega-3 source for triglyceride management. Nonetheless, the biochemical action of its omega-3 content is well established for triglyceride lowering.

In summary, the use of fish liver oil to support high triglyceride treatment is scientifically validated, though with the caveat regarding the specific formulation and safety profile.

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