Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Chicory fiber, also known as inulin, has been studied for its potential to lower triglyceride levels. Inulin is a type of prebiotic soluble fiber derived from chicory root that resists digestion in the upper gastrointestinal tract and is fermented by gut bacteria in the colon. Several small human clinical studies have evaluated the effects of inulin supplementation on blood lipid profiles. Some trials suggest that inulin may help lower serum triglycerides, especially in individuals with mildly elevated levels, by reducing hepatic (liver) synthesis of triglycerides and altering lipid metabolism. The proposed mechanisms include modulation of gut microbiota, increased production of short-chain fatty acids, and improved insulin sensitivity, all of which may contribute to reduced triglyceride synthesis in the liver.

However, the overall quality and quantity of the evidence are limited. Meta-analyses and systematic reviews of randomized controlled trials have generally found a modest but statistically significant reduction in serum triglycerides with inulin supplementation, particularly at higher doses (≥10 g/day) and in people with metabolic syndrome or type 2 diabetes. The effect size tends to be small, and not all studies have found significant benefits. Most research indicates little or no effect on LDL or HDL cholesterol. The evidence is not strong enough for inulin to be considered a primary or stand-alone therapy for hypertriglyceridemia, but it may offer some support as part of a broader dietary approach. In summary, there is scientific evidence supporting the use of chicory fiber for high triglycerides, but its effect is modest and the evidence base is not robust.

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