Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Capsiate is a non-pungent capsaicinoid found in "CH-19 Sweet" peppers, structurally related to capsaicin. Several small-scale human and animal studies have investigated its potential metabolic effects, including its impact on triglyceride levels. Capsiate is thought to promote thermogenesis and increase energy expenditure, mechanisms that could theoretically influence lipid metabolism. Some animal studies have demonstrated that capsiate supplementation can decrease plasma triglyceride levels, possibly by upregulating genes involved in fatty acid oxidation and downregulating those involved in lipogenesis.

In humans, evidence is limited and generally of low quality. A few randomized controlled trials have suggested that capsiate supplementation may slightly reduce postprandial triglyceride levels or improve lipid profiles when combined with exercise or calorie restriction. However, these effects are modest, and the studies often suffer from small sample sizes, short durations, and potential bias. Systematic reviews and meta-analyses of capsaicinoids more broadly indicate possible benefits for lipid metabolism, but capsiate-specific data remain sparse.

In summary, there is some scientific rationale and preliminary evidence supporting the use of capsiate for high triglycerides, but the overall strength of evidence is weak (rated 2/5). Larger, better-designed human trials are needed to confirm efficacy and determine clinical relevance.

More about Capsiate
More about Triglycerides (high)

Other ingredients used for Triglycerides (high)

Other health conditions supported by Capsiate

Products containing Capsiate