Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Calamari oil is derived from squid and is rich in omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). The use of marine-derived omega-3s for supporting and reducing high triglyceride levels is well supported in the scientific literature. Multiple large randomized controlled trials and meta-analyses have shown that supplementation with EPA and DHA can significantly lower elevated triglyceride levels, sometimes by 20-50% depending on the dose. The U.S. Food and Drug Administration (FDA) has approved pharmaceutical-grade omega-3 products for the treatment of severe hypertriglyceridemia, and these products are typically derived from fish or marine sources similar to calamari oil.

While fish oil is more commonly studied, calamari oil provides a similar profile of EPA and DHA, and available evidence suggests that its efficacy in lowering triglycerides is likely comparable. One potential advantage of calamari oil is its relatively higher DHA content compared to some fish oils, which may offer additional cardiovascular or cognitive benefits. However, there are fewer direct clinical trials specifically using calamari oil, so much of the evidence is extrapolated from studies on other marine omega-3 sources.

In summary, the use of calamari oil for supporting high triglycerides is grounded in scientific evidence for marine omega-3s, though direct studies on calamari oil are limited. The overall strength of evidence is moderate (rated 3/5) due to the extrapolative nature of the data.

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