Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Nitrous oxide, commonly known as "laughing gas," is scientifically validated for use during tooth extractions and other dental procedures. Its primary role is as an inhaled sedative and anxiolytic, providing minimal to moderate sedation while maintaining patient consciousness and protective reflexes. The use of nitrous oxide in dentistry dates back to the mid-19th century, and it is now a standard practice in dental offices worldwide. Numerous clinical studies and guidelines from organizations such as the American Dental Association (ADA) and the American Academy of Pediatric Dentistry (AAPD) support its efficacy and safety profile. Nitrous oxide is rapidly acting, has a quick recovery time, and is associated with few side effects, making it ideal for managing dental anxiety, reducing pain perception, and facilitating cooperation, especially in pediatric or anxious patients. It is not an anesthetic in the strict sense but is often used in combination with local anesthesia to provide an optimal patient experience during procedures such as tooth extraction. Systematic reviews consistently show that nitrous oxide provides significant anxiolytic and analgesic benefits with a low risk of complications when administered by trained professionals. Thus, its use in tooth extraction is strongly supported by scientific evidence.

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