Pistacia integerrima gall, known as "kakar singhi" in traditional Ayurvedic and Unani systems, has a long history of use for various respiratory and throat-related ailments, including tonsillitis and sore throat. In these systems, powdered galls are often formulated into syrups, lozenges, or decoctions intended to soothe throat irritation, reduce inflammation, and act as an antimicrobial agent. The traditional rationale stems from the astringent, anti-inflammatory, and purported expectorant properties of the galls.

While there are some in vitro and animal studies suggesting that extracts from Pistacia integerrima galls possess antimicrobial and anti-inflammatory activities, direct clinical evidence supporting their efficacy specifically for tonsillar conditions in humans is lacking. The traditional uses are well-documented in various pharmacopeias and ethnobotanical records, but rigorous modern trials evaluating outcomes such as relief of tonsillitis symptoms or reduction in tonsil size are not currently available. Thus, the support for using Pistacia integerrima gall for tonsillar health is primarily based on traditional use rather than robust scientific validation.

In summary, while traditional medicine strongly endorses the use of Pistacia integerrima gall for throat and tonsil health, current clinical evidence is insufficient, and further research is needed to confirm its effectiveness and safety for this specific application.