Evidence supporting the use of: Scrophularia root
For the body system: Thyroid Gland

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Scrophularia root (from the genus Scrophularia, commonly known as figwort) has been used in traditional Chinese medicine (TCM) and some European herbal practices for centuries. In TCM, Scrophularia (known as Xuan Shen) is classified as a "cooling" herb and is said to "nourish yin," "clear heat," and "dissipate nodules," which includes use for conditions interpreted in modern terms as thyroid swelling or goiter. Historically, herbalists noted its application for "scrofula" (lymphatic gland swellings, including those thought to be related to thyroid issues).

However, there is limited scientific research specifically validating its effectiveness for thyroid health or function. The few available in vitro and animal studies focus mainly on its anti-inflammatory and immunomodulatory effects, with little to no direct evidence regarding thyroid hormone balance or thyroid gland physiology. Modern clinical studies in humans for thyroid support are lacking. Thus, its reputation for supporting the thyroid derives almost entirely from traditional systems and anecdotal historical use rather than validated modern research.

In summary, Scrophularia root's use for thyroid support is justified primarily by tradition, with a low evidence rating due to the absence of robust scientific validation.

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