Evidence supporting the use of: Lactobacillus salivarius
For the health condition: Thrush

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus salivarius is a probiotic bacterium that has been studied for its potential role in supporting the treatment and prevention of oral candidiasis, commonly known as Thrush, which is primarily caused by Candida albicans. The scientific rationale for its use is rooted in the general antagonistic effects that certain probiotic strains, including various Lactobacillus species, exert against pathogenic microorganisms.

Some in vitro studies have shown that L. salivarius can inhibit the growth and adhesion of C. albicans by producing lactic acid and bacteriocins, which lower the pH and create an environment unfavorable for yeast proliferation. Additionally, L. salivarius may compete with pathogens for adhesion sites on the oral mucosa, further limiting Candida colonization.

However, clinical evidence specifically evaluating L. salivarius for the prevention or treatment of Thrush in humans is limited. Most clinical studies focus on other Lactobacillus strains (such as L. rhamnosus or L. reuteri) or on probiotics as a broader category. A few small clinical trials and case reports suggest potential benefit, but these are not robust enough to draw firm conclusions.

In summary, while laboratory and theoretical evidence supports a possible role for L. salivarius in managing Thrush, current human clinical evidence is limited and does not yet allow for strong recommendations. Thus, the evidence rating is moderate to low at this time.

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