Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus species are probiotics that have been studied for their potential role in the prevention and adjunctive treatment of thrush, also known as oropharyngeal or vaginal candidiasis. The scientific rationale is based on the ability of Lactobacillus to compete with Candida species for adhesion sites and nutrients, as well as their production of lactic acid and other antimicrobial substances that can inhibit fungal growth. Some clinical trials and in vitro studies have suggested that certain strains of Lactobacillus, particularly L. rhamnosus and L. reuteri, may help reduce the recurrence of vaginal thrush and restore normal microbiota following antifungal treatment. However, the evidence is inconsistent and often limited by small sample sizes, heterogeneity of strains used, and variations in study design. Systematic reviews and meta-analyses generally conclude that while there is some benefit, especially as an adjunct rather than a replacement for antifungal drugs, the overall quality of evidence is low to moderate. There is also less evidence supporting the use of Lactobacillus for oral thrush compared to vaginal thrush. As such, the use of Lactobacillus for thrush is supported by some scientific studies, but more robust and standardized clinical trials are needed to establish efficacy and optimal strains.

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