Evidence supporting the use of: Cholesterol
For the health condition: Testosterone (low)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cholesterol is a molecular precursor for the synthesis of all steroid hormones, including testosterone. In humans, the Leydig cells in the testes convert cholesterol into testosterone via a series of enzymatic steps. This foundational biochemical relationship is well established in endocrinology. However, the use of dietary cholesterol or cholesterol supplements specifically to treat low testosterone (hypogonadism) is not standard medical practice and remains scientifically unsupported. Clinical studies show that while extremely low cholesterol levels (such as from aggressive statin therapy) might slightly reduce testosterone, dietary cholesterol intake in the context of a normal diet does not generally influence testosterone levels significantly in healthy adults. Most individuals synthesize adequate cholesterol endogenously for hormone production. There is limited evidence suggesting that severe cholesterol deficiency could impair steroidogenesis, but such cases are rare in populations with normal diets. Thus, while there is a scientific basis for cholesterol’s role in testosterone production, supplementing cholesterol is not an evidence-based treatment for low testosterone, and its overall impact on testosterone levels in most people is minimal. Current guidelines for managing low testosterone do not recommend cholesterol supplementation.
Other ingredients used for Testosterone (low)
acetyl l-carnitineashwagandha
boron
DHEA (dehydroepiandrosterone)
maca
magnesium
muira puama
tongkat ali
tribulus
vitamin D3
zinc
cistanche
yohimbe
19-NorAndrost-4ene-3b-ol,17-one
Antler
Anti-aromatase
Bulbine natalensis
Ba Ji Tian
Butea superba
DHEA
D-Aspartic Acid
yohimbine