Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arginine is an amino acid that has been researched for its potential effect on testosterone levels, primarily due to its role as a precursor to nitric oxide, which supports blood flow and vascular health. Some small clinical studies and preclinical experiments have explored whether arginine supplementation can increase testosterone, especially in the context of exercise performance or erectile dysfunction. However, the evidence remains inconsistent and is generally considered weak.

Most research shows that while arginine may help improve blood flow and could play a minor role in supporting sexual function, there is little direct evidence that it substantially increases testosterone levels in healthy men or those with low testosterone. Some animal studies and limited human trials have noted minor increases in testosterone after arginine supplementation, but these effects are typically modest and not consistently replicable. Larger, well-controlled studies are lacking.

Currently, arginine is not broadly recommended by clinical guidelines for the treatment of low testosterone, and any use in this context is often adjunctive or experimental. Its primary scientific validation relates to cardiovascular and erectile health rather than direct hormonal modulation. Thus, the evidence supporting arginine as a treatment for low testosterone is limited, with a rating of 2 out of 5.

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